Water activity of aqueous solutions of ethylene oxide-propylene oxide block copolymers and maltodextrins

Structural Polymorphism of Poly(ethylene oxide)-Poly(propylene oxide) Block Copolymers in Nonaqueous Polar Solvents

The solution properties of water-soluble amphiphiles in nonaqueous polar solvents are important in the elucidation of the effects of solvent quality on self-assembly and also in practical applications where the use of water as a solvent is undesirable. We studied the self-assembly of a poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymer (Pluronic P105: EO37PO58EO37) in formamid...

Intracellular delivery of VEGF165 encoding gene therapeutic using trifunctional copolymers of ethylene oxide and propylene oxide

Poly(ethylene oxide)–Poly(propylene oxide)-Based Copolymers for Transdermal Drug Delivery: An Overview

Amphiphilic poly(ethylene oxide)–poly(propylene oxide) (PEO–PPO)-based copolymers are thermoresponsive materials having aggregation properties in aqueous medium. As hydrosolubilizers of poorly water-soluble drugs and improved stability of sensitive agents, these materials have been investigated for improvement in solubility, stability, release and bioavailability of drugs. The goal of the prese...

Ultrafast infrared heating laser pulse-induced micellization kinetics of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) in water.

The heating-induced micellization of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (Pluronic PE10300) triblock copolymer chains was studied by ultrasensitive differential scanning calorimetry, laser light scattering, and fluorescence spectrometry with a fluorescent probe, 8-anilino-1-naphthalenesulfonic acid ammonium salt. The critical micellization temperatures obtained f...

Drying of films formed by ordered poly(ethylene oxide)-poly(propylene oxide) block copolymer gels.

The drying of hydrogel films formed by poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers (Pluronic P105 and Pluronic L64) is investigated at various air relative humidity (RH) conditions in the range 11-94%. These amphiphilic block copolymers self-assemble to form a variety of ordered (lyotropic liquid crystalline) structures as the water content decreases. The amount of wat...